Yazarlar : Dado D, Sagi M, Levenberg S, Zemel A.

Yayın : Regen Med.

Yayın Yılı : 2011

Pubmed Linki : http://www.ncbi.nlm.nih.gov/pubmed/22168501

Konu : Rejeneratif Tıp

Literatür İçeriği :  Abstract

Numerous studies have focused on identifying the chemical and biological factors that govern the differentiation of stem cells; however, recent research has shown that mechanical cues may play an equally important role. Mechanical forces such as shear stresses and tensile loads, as well as the rigidity and topography of the extracellular matrix were shown to induce significant changes in the morphology and fate of stem cells. We survey experimental studies that focused on the response of stem cells to mechanical and geometrical properties of their environment and discuss the mechanical mechanisms that accompany their response including the remodeling of the cytoskeleton and determination of cell and nucleus size and shape.

Literatür Arşivi

Sunumlar	Videolar	Olgu Tartışması
Incorporating Molecular Data into Risk Stratification for AML	Neden Hematolojiyi seçtim?	Abstract Introduction: Aplastic anemia is a rare disease caused by destruction of pluripotent stem cells in bone marrow. During pregnancy it could be life-threatening for both mother and child. The only causal therapy for aplastic anemia is bone marrow t Novel therapies delay the progression of smoldering multiple myeloma: