Yazarlar : Kurz M, Stoeckle M, Krasniqi F et al

Yayın : Int J STD AIDS

Yayın Yılı : 2014

Pubmed Linki : http://www.docguide.com/etravirine-good-option-concomitant-use-chemotherapy-hodgkins-lymphoma?tsid=5

Konu : Lenfoma

Literatür İçeriği :  The treatment of malignancies in HIV patients is challenged by the issue of drug-drug interactions between antiretroviral therapy and antineoplastic agents. While protease inhibitors have been shown to increase the incidence and severity of cancer therapy-related side effects, the impact of other antiretroviral agents on the tolerability and response to chemotherapy is less well documented. We report the successful use of an etravirine-based regimen in a patient treated with BEACOPP chemotherapy for advanced Hodgkin's lymphoma. Etravirine constitutes a valuable option for concomitant use with chemotherapy due to its moderate inducing effect on drug metabolising enzymes.

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