| Literatürler Hematoloji Uzmanlık Derneği
Literatür Detay Bilgisi
Towards an ideal source of mesenchymal stem cell isolation for possible therapeutic application inregenerative medicine.

Yazarlar : Bellavia M, Altomare R, Cacciabaudo F, Santoro A, Allegra A, Concetta Gioviale M, Lo Monte AI.

Yayın : Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

Yayın Yılı : 2013

Konu : Rejeneratif Tıp

Literatür İçeriği :

BACKGROUND:

The possibility of obtaining mesenchymal stem cells (MSCs) from fetal tissue such as amniotic fluid, chorionic villi and placenta is well-known and a comparison between MSCs originating in different sources such as fetal tissue and those from bone marrow in terms of yield and function is a topical issue. The mesenchymal stem cells isolated from bone marrow are well-characterized. Unfortunately the low quantitative yield during isolation is a major problem. For this reason, other tissue sources for MSCs are of paramount importance.

CONCLUSION:

In this review, starting from a description of the molecular and cellular biology of MSCs, we describe alternative sources of isolation other than bone marrow. Finally, we describe the potential therapeutic application of these cells.


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