| Literatürler Hematoloji Uzmanlık Derneği
Literatür Detay Bilgisi
Dedifferentiation, transdifferentiation, and reprogramming: future directions in regenerative medicine

Yazarlar : Eguizabal C, Montserrat N, Veiga A, Izpisua Belmonte JC

Yayın : Semin Reprod Med

Yayın Yılı : 2013

Konu : Rejeneratif Tıp

Literatür İçeriği :

The main goal of regenerative medicine is to replace damaged tissue. To do this it is necessary to understand in detail the whole regeneration process including differentiated cells that can be converted into progenitor cells (dedifferentiation), cells that can switch into another cell type (transdifferentiation), and somatic cells that can be induced to become pluripotent cells (reprogramming). By studying the regenerative processes in both nonmammal and mammal models, natural or artificial processes could underscore the molecular and cellular mechanisms behind these phenomena and be used to create future regenerative strategies for humans.

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