Yazarlar : McNamara LE, Sjöström T, Meek RM, Oreffo RO, Su B, Dalby MJ, Burgess KE.

Yayın : Attal M, Lauwers-Cances V, Marit G,et al

Yayın Yılı : 2012

Pubmed Linki : http://www.ncbi.nlm.nih.gov/pubmed/22571202

Konu : Kemik İliği Nakli

Literatür İçeriği :  

Abstract

Metabolomics is a method for investigation of changes in the global metabolite profile of cells. This paper discusses the technical application of the approach, considering metabolite extraction, separation, mass spectrometry and data interpretation. A particular focus is on the application of metabolomics to the study of stem cell physiology in the context of biomaterials and regenerative medicine. Case studies are used to illustrate key points, focusing on the use of metabolomics in the examination of mesenchymal stem cell responses to titania-nanopillared substrata designed for orthopaedic applications.

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